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Antoinette Brush's avatar

My family doc nearly refused my request for vitamin D level, she acquiesced and then as my result was 70 ( I’ve been actively working on elevating it) told me to stop supplementation. A “D” level should be routine with every annual physical. But when advised to stop supplementation, by a mask wearing doc ( who should know better) it’s hard to take any of her advice seriously. I need a new doc 🤷‍♀️

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Robin Whittle's avatar

Thanks Simon! This page https://vitamindstopscovid.info/00-evi/ cites and discusses the most pertinent research on vitamin D and the immune system.

This includes how much vitamin D3 to take a day, on average (up to 10 days between intakes is OK) according to bodyweight and some health conditions, especially obesity which reduces the ability to raise circulating 25-hydroxyvitamin D for any vitamin D3 intake as a ratio of bodyweight: https://vitamindstopscovid.info/00-evi/index.html#sjw-updated-ratios .

To raise the circulating 25-hydroxyvitamin D level safely over 50 ng/mL 125 nmol/L in clinical emergencies such as COVID-19, sepsis, Kawasaki disease, MIS-C, severe influenza - or any acute illness - a single oral dose of 1mg calcefediol (which _is_ 25-hydroxyvitamin D) for 70 kg bodyweight will do this in 4 hours. Bolus 10m 400,000 IU vitamin D3 takes about 4 days due to the need for hydroxylation in the liver. Ordinary healthy intakes such as 0.125 mg 5000 IU vitamin D3 a day take months to raise the 25-hydroxyvitamin D from typical unsupplemented levels of 5 to 25 ng/mL to 50 ng/mL. See: Professor Sunil Wimalawansa's recent article in Nutrients: https://www.mdpi.com/2072-6643/14/14/2997, https://nutritionmatters.substack.com/p/calcifediol-25-hydroxyvitamin-d-or and https://vitamindstopscovid.info/04-calcifediol/ .

Nothing is more important than raising your circulating 25-hydroxvyvitamin D level to 50 ng/mL 125 nmol/L, which is what the immune system needs to work properly, including reducing the risk of excessive inflammation.

See: https://vitamindstopscovid.info/06-adv/ on the Coimbra protocol (higher vitamin D3 intakes) to suppress the excessive inflammation which causes auto-immune disorders such as psoriasis, MS and rheumatoid arthritis. This excessively strong immune response evolved in our ancestors to counter the inflammation down-modulating compounds emitted by helminths (intestinal worms), which infected most or all of our ancestors all the time. Now we are dewormed, our inflammatory responses are often too strong. Helminthic therapy involves deliberately being infected with intestinal worms to suppress these inflammatory diseases: https://helminthictherapywiki.org/

The vitamin D people know nothing about helminths and the helminthic people do not seem to think about vitamin D.

If most or all people had 50 ng/mL or more circulating vitamin D3 humanity's burden of ill-health would be, very approximately, halved. There would only be occasional influenza and COVID-19 infections. There would be no pandemic spread, and those infected would rarely develop severe symptoms.

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